Abstract
Aim: To evaluate if there is a difference in the clinical course of primary vitreoretinal lymphoma (PVRL) in vitrectomized versus non-vitrectomized eyes. Methods: Observational multicenter retrospective case series of patients diagnosed with PVRL between 2007 and 2019, at three tertiary centers. The main outcomes were relapse rates, inflammatory parameters, and best-corrected visual acuities (BCVA). Statistical methods used were an adjusted generalized estimating equation model, and a proportional Cox model. Results: Eighty patients (150 eyes) were followed for a median of 1.7 years. At presentation, there were no clinical differences between the groups. The relapse rate was 0.091/eye-year (EY) for vitrectomized eyes and 0.087/EY for non-vitrectomized eyes (p = .35). Vitrectomized eyes had better BCVA than non-vitrectomized eyes (p < .001). Conclusions: Vitrectomy had no effect on the relapse rate in eyes with PVRL. However, the decrease in vitreous cell and debris led to vitrectomized eyes having better visual acuity than non-vitrectomized eyes.
Original language | English (US) |
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Pages (from-to) | 496-500 |
Number of pages | 5 |
Journal | Ocular Immunology and Inflammation |
Volume | 31 |
Issue number | 3 |
DOIs | |
State | Published - 2023 |
Keywords
- Primary vitreoretinal lymphoma
- ocular lymphoma
- vitrectomy
ASJC Scopus subject areas
- Ophthalmology
- Immunology and Allergy