TY - JOUR
T1 - Clinical Outcomes following Percutaneous Urinary Diversion for Hemorrhagic Cystitis
AU - Farhan, Ahmed
AU - Lyons, Gray R.
N1 - Funding Information:
The authors thank all patients and their families who contributed to this study.
Publisher Copyright:
© 2022 SIR
PY - 2022/7
Y1 - 2022/7
N2 - Hemorrhagic cystitis (HC) can lead to severe morbidity in treatment-refractory cases. Percutaneous nephrostomy (PCN) drainage was first described in 1993 as a safe, nonoperative procedure to achieve supravesical urinary diversion and treat severe HC. Despite its early success, subsequent studies in the adult population have been limited. This retrospective case series describes long-term outcomes following PCN placement in 24 patients with refractory HC. The overall technical success of the procedure was 100%. Seventeen of 24 (71%) patients experienced resolution of hematuria. The median time for hematuria resolution after the procedure was 12 days (interquartile range, 7–28 days). Postprocedural HC severity grade significantly decreased from a median Grade 3 to Grade 1 (P <.01). The complications included catheter obstruction, dislodgement, and associated urinary tract infections occurring at rates of 1.0, 1.6, and 1.7 per 1,000 catheter days, respectively. This study of PCN placement demonstrated and further confirmed the effectiveness of urinary diversion in treating refractory HC.
AB - Hemorrhagic cystitis (HC) can lead to severe morbidity in treatment-refractory cases. Percutaneous nephrostomy (PCN) drainage was first described in 1993 as a safe, nonoperative procedure to achieve supravesical urinary diversion and treat severe HC. Despite its early success, subsequent studies in the adult population have been limited. This retrospective case series describes long-term outcomes following PCN placement in 24 patients with refractory HC. The overall technical success of the procedure was 100%. Seventeen of 24 (71%) patients experienced resolution of hematuria. The median time for hematuria resolution after the procedure was 12 days (interquartile range, 7–28 days). Postprocedural HC severity grade significantly decreased from a median Grade 3 to Grade 1 (P <.01). The complications included catheter obstruction, dislodgement, and associated urinary tract infections occurring at rates of 1.0, 1.6, and 1.7 per 1,000 catheter days, respectively. This study of PCN placement demonstrated and further confirmed the effectiveness of urinary diversion in treating refractory HC.
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U2 - 10.1016/j.jvir.2022.03.605
DO - 10.1016/j.jvir.2022.03.605
M3 - Article
C2 - 35777893
AN - SCOPUS:85129920946
SN - 1051-0443
VL - 33
SP - 841
EP - 844
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 7
ER -