Clinical outcomes after thrombectomy for acute ischemic stroke on weekends versus weekdays

Ali Saad, Malik Muhammad Adil, Vikas Patel, Kumiko Owada, Melanie J. Winningham, Fadi Nahab

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Background: The objective of this study was to determine whether clinical outcomes differed in acute ischemic stroke (AIS) patients who underwent thrombectomy on weekends versus weekdays. Methods: Patients with a primary diagnosis of AIS who underwent thrombectomy were identified from the Nationwide Inpatient Sample from 2005 to 2011 and stratified according to weekend or weekday admission. Logistic regression analysis was performed to identify factors associated with moderate-to-severe disability at hospital discharge in teaching and nonteaching hospitals. Results: Of 12,055 patients with AIS who underwent thrombectomy during the study period, 2862 (23.7%)were admitted on a weekend. In a multivariate logistic regression analysis, factors associated withmoderate or severe disability at discharge in nonteaching hospitals were weekend admission (odds ratio [OR], 1.6; 95% confidence interval [CI], 1.0-2.8; P = .04), diagnosis of hypertension (OR, 1.9; 95% CI, 1.0-3.6; P = .05), and Medicare or Medicaid insurance status (OR, 2.1; 95% CI 1.1- 4.3; P = .02); factors associated with moderate or severe disability at discharge in teaching hospitals were age > 70 years (OR, 1.5; 95% CI, 1.1-2.2; P =.02), pneumonia (OR, 4.7; 95% CI, 2.2-10.2; P < 0001), sepsis (OR, 8.2; 95% CI, 1.2-54.8; P =.03), intracranial hemorrhage (OR, 3.3; 95% CI, 1.8-6.1; P =.0001), and treatment in a Northwest hospital region (OR, 1.7; 95% CI, 1.2-2.4; P = .03). Conclusions: AIS patients undergoing thrombectomy who were admitted to nonteaching hospitals on weekendsweremore likely to be dischargedwithmoderate-to-severe disability than those admitted onweekdays. No weekend effect on discharge clinical outcome was seen in teaching hospitals.

Original languageEnglish (US)
Pages (from-to)2708-2713
Number of pages6
JournalJournal of Stroke and Cerebrovascular Diseases
Issue number10
StatePublished - 2014
Externally publishedYes


  • All cerebrovascular disease/stroke
  • Endovascular therapy
  • Harm/risk analysis
  • Infarction
  • Thrombectomy
  • Weekend effect

ASJC Scopus subject areas

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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