Clinical outcome after complete or partial cortical resection for intractable epilepsy

E. Wyllie, H. Lüders, H. H. Morris, R. P. Lesser, D. S. Dinner, J. Hahn, M. L. Estes, A. D. Rothner, G. Erenberg, R. Cruse, D. Friedman

Research output: Contribution to journalArticlepeer-review

152 Scopus citations


This is the first epilepsy surgery series to analyze the definition of “completeness” of resection, based solely on results of chronic scalp and subdural EEG recording. When patients had complete removal of all cortical areas with ictal and interictal epileptiform discharges, the clinical outcome was usually good. When areas with epileptiform discharges were left behind, good outcome was significantly less frequent. This correlation between complete resection and good outcome was independent of the presence or absence of CT-detected structural lesions or sharp waves on post-resection electrocorticography. These results support completeness of resection, defined by prolonged extraoperative EEG, as an important factor in seizure surgery.

Original languageEnglish (US)
Pages (from-to)1634-1641
Number of pages8
Issue number10
StatePublished - Oct 1987
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology


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