Clinical laboratory stressors used to study alcohol-stress relationships

Suzanne Thomas, Amy K. Bacon, Rajita Sinha, Magdalena Uhart, Bryon Adinoff

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Understanding the biologic systems that underlie the relationship between stress and alcohol consumption may lead to better prevention efforts and more effective treatments for alcoholism. Clinical laboratory studies offer a unique opportunity to examine these relationships by using a controlled environment to study how an acute stressor affects alcohol driving and alcohol craving, how individuals in recovery or those at risk for alcoholism may respond differently to stressors relative to control subjects, and how alcohol differentially affects stress reactivity in these groups. This article reviews some of the most common physical, psychological, and pharmacological stressors used in stress-induction studies designed to reveal details about the relationship between stress reactivity and alcohol use and abuse.

Original languageEnglish (US)
Pages (from-to)459-467
Number of pages9
JournalAlcohol Research: Current Reviews
Issue number4
StatePublished - 2012
Externally publishedYes


  • Alcohol consumption
  • Alcohol use and abuse
  • Alcoholism
  • Biological adaptation to stress
  • Clinical study
  • Controlled study
  • Laboratory study
  • Pharmacological stressor
  • Physiological stressor
  • Psychological stressor
  • Stress
  • Stress reactivity
  • Stress-induction study
  • Stressor

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Clinical Psychology
  • Psychiatry and Mental health


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