Clinical interventions to break the obesity and cancer link: a narrative review

Research output: Contribution to journalReview articlepeer-review


Excess body weight is a significant risk factor for the development and recurrence of many types of cancer. Patients with a history or current diagnosis of cancer who are overweight or have obesity have an increased risk of cancer treatment-related morbidity, recurrence, and decreased quality of life. Weight loss and maintenance of a healthy body weight may reduce cancer morbidity and recurrence in cancer survivors. While guidelines for cancer survivorship elaborate sufficiently on lifestyle interventions, little guidance is provided when considering additional therapies like anti-obesity pharmacotherapy or bariatric surgery for weight loss. This review will highlight and address current recommendations and feasible interventions that clinicians may consider to further reduce the incidence and recurrence of cancer in patients with obesity.

Original languageEnglish (US)
Pages (from-to)719-735
Number of pages17
JournalCancer and Metastasis Reviews
Issue number3
StatePublished - Sep 2022


  • Anti-obesity medication
  • Bariatric surgery
  • Cancer
  • Obesity
  • Weight loss

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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