Clinical and experimental immunobiology of medulloblastomas

M. A. Gerosa; G. Semenzato; G. Amadori; A. Olivi; A. Rotilio; M. Zuccarello

Clinical and experimental immunobiology of medulloblastomas

M. A. Gerosa, G. Semenzato, G. Amadori, A. Olivi, A. Rotilio, M. Zuccarello

Research output: Contribution to journal › Article › peer-review

Abstract

A wide pre- and postoperative immunological monitoring of B- and T-cell markers in children with medulloblastomas is presented. Preoperative investigations showed a noticeable failure of T-cell-dependent immunity, currently identified by 'active' E-rosette forming cells (Ea-RFC) and blastogenesis tests, with a significant increase of spontaneous cell-mediated cytotoxicity (SCMC). In postoperative long-term controls, a slight recovery of Ea-RFC and blastogenesis tests was observed. The main findings concerning cytotoxicity kinetics are discussed.

Original language	English (US)
Pages (from-to)	193-195
Number of pages	3
Journal	Surgical neurology
Volume	14
Issue number	3
State	Published - 1980
Externally published	Yes

ASJC Scopus subject areas

Surgery
Clinical Neurology

Cite this

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abstract = "A wide pre- and postoperative immunological monitoring of B- and T-cell markers in children with medulloblastomas is presented. Preoperative investigations showed a noticeable failure of T-cell-dependent immunity, currently identified by 'active' E-rosette forming cells (Ea-RFC) and blastogenesis tests, with a significant increase of spontaneous cell-mediated cytotoxicity (SCMC). In postoperative long-term controls, a slight recovery of Ea-RFC and blastogenesis tests was observed. The main findings concerning cytotoxicity kinetics are discussed.",

author = "Gerosa, {M. A.} and G. Semenzato and G. Amadori and A. Olivi and A. Rotilio and M. Zuccarello",

year = "1980",

language = "English (US)",

volume = "14",

pages = "193--195",

journal = "World Neurosurgery",

issn = "1878-8750",

publisher = "Elsevier Inc.",

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T1 - Clinical and experimental immunobiology of medulloblastomas

AU - Gerosa, M. A.

AU - Semenzato, G.

AU - Amadori, G.

AU - Olivi, A.

AU - Rotilio, A.

AU - Zuccarello, M.

PY - 1980

Y1 - 1980

N2 - A wide pre- and postoperative immunological monitoring of B- and T-cell markers in children with medulloblastomas is presented. Preoperative investigations showed a noticeable failure of T-cell-dependent immunity, currently identified by 'active' E-rosette forming cells (Ea-RFC) and blastogenesis tests, with a significant increase of spontaneous cell-mediated cytotoxicity (SCMC). In postoperative long-term controls, a slight recovery of Ea-RFC and blastogenesis tests was observed. The main findings concerning cytotoxicity kinetics are discussed.

AB - A wide pre- and postoperative immunological monitoring of B- and T-cell markers in children with medulloblastomas is presented. Preoperative investigations showed a noticeable failure of T-cell-dependent immunity, currently identified by 'active' E-rosette forming cells (Ea-RFC) and blastogenesis tests, with a significant increase of spontaneous cell-mediated cytotoxicity (SCMC). In postoperative long-term controls, a slight recovery of Ea-RFC and blastogenesis tests was observed. The main findings concerning cytotoxicity kinetics are discussed.

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M3 - Article

C2 - 6968987

AN - SCOPUS:0018954483

SN - 1878-8750

VL - 14

SP - 193

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JO - World Neurosurgery

JF - World Neurosurgery

IS - 3

ER -

Clinical and experimental immunobiology of medulloblastomas

Abstract

ASJC Scopus subject areas

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