Clean cord care practices and neonatal mortality: Evidence from rural Uttar Pradesh, India

Praween K. Agrawal, Sutapa Agrawa, Luke C Mullany, Gary L. Darmstadt, Vishwajeet Kumar, Usha Kiran, Ramesh C. Ahuja, Vinod K. Srivastava, Mathuram Santosham, Robert E. Black, Abdullah H. Baqui

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Background About a million newborns die each year in India, accounting for about a fourth of total global neonatal deaths. Infections are among the leading causes of neonatal mortality. Care practices immediately following delivery contribute to newborns' risk of infection and mortality. Objectives This study examined the association between clean cord care practices and neonatal mortality in rural Uttar Pradesh, India. Methods The study used data from a household survey conducted to evaluate a community-based intervention program in two districts of Uttar Pradesh, India. Analysis included data from 5741 singleton live births delivered at home during 2005. The association between clean cord care (clean instrument used to cut cord, clean thread used to tie cord and antiseptics or nothing applied to the cord) and neonatal mortality was estimated using multivariate logistic regression models. Results Thirty per cent of the study mothers practiced clean cord care. Neonatal mortality rate was significantly lower among newborns exposed to clean cord care (36.5/1000 live births, 95% CI 28.0 to 46.8) than those who did not practice (53.0/1000 live births, 95% CI 46.1 to 60.6). Clean cord care was associated with 37% lower neonatal mortality (OR=;0.63; 95% CI 0.46 to 0.87) after adjusting for mother's age, education, caste/tribe, religion, household wealth, newborn thermal care practice and care-seeking during the first week after birth and study arms. Conclusions Promoting clean cord care practice among neonates in community-based maternal and newborn care programs has the potential to improve neonatal survival in rural India and similar other settings.

Original languageEnglish (US)
Pages (from-to)755-758
Number of pages4
JournalJournal of epidemiology and community health
Issue number8
StatePublished - Aug 2012

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health


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