Circulating candida enolase in invasive candidiasis

John R. Wingard, Ruth Matthews, James Burnie, Thomas J. Walsh, Philip A. Pizzo

Research output: Contribution to journalLetterpeer-review


To the Editor: The data presented by Walsh et al. (April 11 issue)* assess the potential of a new test to document deep-seated candida infections. This assay appears to provide information complementary to that supplied by currently available tests. An important consideration in determining the test's usefulness in clinical practice is how early the results first become positive in relation to the time it takes to document infection according to standard criteria. From the discussion, it appears that the enolase antigen was detected in only 6 of the 24 infected patients before cultures became positive. Moreover, another six infected patients. .

Original languageEnglish (US)
Pages (from-to)1446-1447
Number of pages2
JournalNew England Journal of Medicine
Issue number20
StatePublished - Nov 14 1991
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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