Chronic Spontaneous Urticaria. Etiology and Pathogenesis

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77 Scopus citations


Urticaria affects individuals of all ages and is commonplace. Nearly 1 in 5 individuals will experience an episode of urticaria in their lifetime, while the chronic form of disease has an estimated annual prevalence of approximately 1% of the population. Given the similarity of chronic urticaria symptoms to those seen in patients suffering an allergic reaction, the condition often leads to a search for an external cause. In most cases, no external trigger factor is identified. At present several theories of pathogenesis exist, none of which is firmly established.

Original languageEnglish (US)
Pages (from-to)33-52
Number of pages20
JournalImmunology and Allergy Clinics of North America
Issue number1
StatePublished - Feb 1 2014


  • Basophils
  • Chronic urticaria
  • Mast cells

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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