Chronic pulmonary histoplasmosis: improved lymphocyte response with transfer factor

C. R. Smith; D. E. Griffin; J. R. Graybill

doi:10.7326/0003-4819-84-6-708

Chronic pulmonary histoplasmosis: improved lymphocyte response with transfer factor

C. R. Smith, D. E. Griffin, J. R. Graybill

Bloomberg School of Public Health

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Abstract

Infection with Histoplasma capsulatum may cause chronic cavitary pulmonary disease in humans. Approximately 12% to 17% of patients with chronic pulmonary histoplasmosis have an impaired cell mediated immune response to histoplasmin. It has been suggested that this impairment may be reversed by transfer factor. The authors gave 3 U of transfer factor to a patient with anergic chronic pulmonary histoplasmosis and observed transient conversion of his skin test and lymphocyte transformation index (LTI).

Original language	English (US)
Pages (from-to)	708-709
Number of pages	2
Journal	Annals of internal medicine
Volume	84
Issue number	6
DOIs	https://doi.org/10.7326/0003-4819-84-6-708
State	Published - 1976

ASJC Scopus subject areas

Internal Medicine

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abstract = "Infection with Histoplasma capsulatum may cause chronic cavitary pulmonary disease in humans. Approximately 12% to 17% of patients with chronic pulmonary histoplasmosis have an impaired cell mediated immune response to histoplasmin. It has been suggested that this impairment may be reversed by transfer factor. The authors gave 3 U of transfer factor to a patient with anergic chronic pulmonary histoplasmosis and observed transient conversion of his skin test and lymphocyte transformation index (LTI).",

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AU - Griffin, D. E.

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AB - Infection with Histoplasma capsulatum may cause chronic cavitary pulmonary disease in humans. Approximately 12% to 17% of patients with chronic pulmonary histoplasmosis have an impaired cell mediated immune response to histoplasmin. It has been suggested that this impairment may be reversed by transfer factor. The authors gave 3 U of transfer factor to a patient with anergic chronic pulmonary histoplasmosis and observed transient conversion of his skin test and lymphocyte transformation index (LTI).

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Chronic pulmonary histoplasmosis: improved lymphocyte response with transfer factor

Abstract

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