Chronic myelogenous leukemia

Susan O'Brien; Ellin Berman; Kapil Bhalla; Edward A. Copelan; Marcel P. Devetten; Peter D. Emanuel; Harry P. Erba; Peter L. Greenberg; Joseph O. Moore; Donna Przepiorka; Jerald P. Radich; Russell J. Schilder; Paul Shami; B. Douglas Smith; David S. Snyder; Robert J. Soiffer; Martin S. Tallman; Moshe Talpaz; Meir Wetzler

doi:10.6004/jnccn.2007.0043

Chronic myelogenous leukemia

Susan O'Brien, Ellin Berman, Kapil Bhalla, Edward A. Copelan, Marcel P. Devetten, Peter D. Emanuel, Harry P. Erba, Peter L. Greenberg, Joseph O. Moore, Donna Przepiorka, Jerald P. Radich, Russell J. Schilder, Paul Shami, B. Douglas Smith, David S. Snyder, Robert J. Soiffer, Martin S. Tallman, Moshe Talpaz, Meir Wetzler

School of Medicine

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Chronic myelogenous leukemia (CML) accounts for 15% of adult leukemias. In 2007, an estimated 4500 cases will be diagnosed and 900 patients will die of the disease. The goal of CML therapy is complete remission, which typically progresses from hematologic to cytogenetic remission. These updated 2007 guidelines include changes to several treatment recommendations, including considerations for imatinib dosing, the use of interferon, and management of dasatinib toxicity. Recommendations for hematopoetic stem cell transplantation have also been updated.

Original language	English (US)
Pages (from-to)	474-496
Number of pages	23
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	5
Issue number	5
DOIs	https://doi.org/10.6004/jnccn.2007.0043
State	Published - May 2007

Keywords

Chronic myelogenous leukemia
Desatinib
Imatinib
Karyotyping
NCCN clinical practice guidelines
Polymerase chain reaction
Transplantation

ASJC Scopus subject areas

Oncology

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10.6004/jnccn.2007.0043

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O'Brien, S., Berman, E., Bhalla, K., Copelan, E. A., Devetten, M. P., Emanuel, P. D., Erba, H. P., Greenberg, P. L., Moore, J. O., Przepiorka, D., Radich, J. P., Schilder, R. J., Shami, P., Smith, B. D., Snyder, D. S., Soiffer, R. J., Tallman, M. S., Talpaz, M., & Wetzler, M. (2007). Chronic myelogenous leukemia. JNCCN Journal of the National Comprehensive Cancer Network, 5(5), 474-496. https://doi.org/10.6004/jnccn.2007.0043

O'Brien, S, Berman, E, Bhalla, K, Copelan, EA, Devetten, MP, Emanuel, PD, Erba, HP, Greenberg, PL, Moore, JO, Przepiorka, D, Radich, JP, Schilder, RJ, Shami, P, Smith, BD, Snyder, DS, Soiffer, RJ, Tallman, MS, Talpaz, M & Wetzler, M 2007, 'Chronic myelogenous leukemia', JNCCN Journal of the National Comprehensive Cancer Network, vol. 5, no. 5, pp. 474-496. https://doi.org/10.6004/jnccn.2007.0043

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abstract = "Chronic myelogenous leukemia (CML) accounts for 15% of adult leukemias. In 2007, an estimated 4500 cases will be diagnosed and 900 patients will die of the disease. The goal of CML therapy is complete remission, which typically progresses from hematologic to cytogenetic remission. These updated 2007 guidelines include changes to several treatment recommendations, including considerations for imatinib dosing, the use of interferon, and management of dasatinib toxicity. Recommendations for hematopoetic stem cell transplantation have also been updated.",

keywords = "Chronic myelogenous leukemia, Desatinib, Imatinib, Karyotyping, NCCN clinical practice guidelines, Polymerase chain reaction, Transplantation",

author = "Susan O'Brien and Ellin Berman and Kapil Bhalla and Copelan, {Edward A.} and Devetten, {Marcel P.} and Emanuel, {Peter D.} and Erba, {Harry P.} and Greenberg, {Peter L.} and Moore, {Joseph O.} and Donna Przepiorka and Radich, {Jerald P.} and Schilder, {Russell J.} and Paul Shami and Smith, {B. Douglas} and Snyder, {David S.} and Soiffer, {Robert J.} and Tallman, {Martin S.} and Moshe Talpaz and Meir Wetzler",

year = "2007",

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doi = "10.6004/jnccn.2007.0043",

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AU - Berman, Ellin

AU - Bhalla, Kapil

AU - Copelan, Edward A.

AU - Devetten, Marcel P.

AU - Emanuel, Peter D.

AU - Erba, Harry P.

AU - Greenberg, Peter L.

AU - Moore, Joseph O.

AU - Przepiorka, Donna

AU - Radich, Jerald P.

AU - Schilder, Russell J.

AU - Shami, Paul

AU - Smith, B. Douglas

AU - Snyder, David S.

AU - Soiffer, Robert J.

AU - Tallman, Martin S.

AU - Talpaz, Moshe

AU - Wetzler, Meir

PY - 2007/5

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AB - Chronic myelogenous leukemia (CML) accounts for 15% of adult leukemias. In 2007, an estimated 4500 cases will be diagnosed and 900 patients will die of the disease. The goal of CML therapy is complete remission, which typically progresses from hematologic to cytogenetic remission. These updated 2007 guidelines include changes to several treatment recommendations, including considerations for imatinib dosing, the use of interferon, and management of dasatinib toxicity. Recommendations for hematopoetic stem cell transplantation have also been updated.

KW - Chronic myelogenous leukemia

KW - Desatinib

KW - Imatinib

KW - Karyotyping

KW - NCCN clinical practice guidelines

KW - Polymerase chain reaction

KW - Transplantation

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Chronic myelogenous leukemia

Abstract

Keywords

ASJC Scopus subject areas

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