Chronic active hepatitis in dogs associated with leptospires.

L. Bishop, J. D. Strandberg, R. J. Adams, D. G. Brownstein, R. Patterson

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Chronic active hepatitis was diagnosed in five American Foxhounds from one kennel. Spirochetes were demonstrated in the liver in four of the dogs. A rising titer to Leptospira interrogans serovar grippotyphosa was found in the fifth dog, although spirochetes were not demonstrated in tissues. A serologic survey at the kennel revealed evidence of exposure of 6 of 13 dogs to grippotyphosa. This is the first report of an association between chronic active hepatitis leptospiral infection in any species.

Original languageEnglish (US)
Pages (from-to)839-844
Number of pages6
JournalAmerican journal of veterinary research
Issue number6
StatePublished - Jun 1979
Externally publishedYes

ASJC Scopus subject areas

  • General Veterinary


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