Choroidal neovascularization

Peter A. Campochiaro, Frances E. Kane

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Choroidal neovascularization (CNV) is one of the most challenging problems faced by retina specialists. It is a common cause of severe visual loss in patients with age-related macular degeneration (AMD) and younger patients with one of many diseases that affect the choroid–Bruch’s membrane–retinal pigmented epithelium (RPE) complex, including but not limited to ocular histoplasmosis, myopic degeneration, angioid streaks, and multifocal choroiditis. Current treatments are aimed at destroying CNV. However, even when ablative treatments are initially successful, they are plagued by high rates of recurrences, because they do not address underlying angiogenic stimuli (1). Understanding of the molecular signals involved in the occurrence of CNV could provide the basis for the development of new effective treatments.

Original languageEnglish (US)
Title of host publicationAge-Related Macular Degeneration
PublisherCRC Press
Number of pages10
ISBN (Electronic)9780203909157
ISBN (Print)9780824706821
StatePublished - Jan 1 2002

ASJC Scopus subject areas

  • General Medicine


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