Abstract
Two monoclonal antibodies to choline acetyltransferase (ChAT) were used to stain the cerebral cortex of fetal monkeys at 110-150 days post-conception. In addition to a small number of immunostained fibers, cells resembling typical non-pyramidal neurons were immunostained in developing layers V and VI and in the subjacent white matter of each area examined (sensory-motor and visual areas). ChAT-immunoreactive neurons have not been described in the cerebral cortex of adult primates, but the present observations indicate such neurons exist in the developing primate cortex.
Original language | English (US) |
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Pages (from-to) | 313-317 |
Number of pages | 5 |
Journal | Developmental Brain Research |
Volume | 37 |
Issue number | 1-2 |
DOIs | |
State | Published - Dec 15 1987 |
Externally published | Yes |
Keywords
- Acetylcholine
- Cerebral cortex
- Immunocytochemistry
- Non-pyramidal neuron
ASJC Scopus subject areas
- Developmental Neuroscience
- Developmental Biology