Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex

S. H.C. Hendry; E. G. Jones; H. P. Killackey; L. M. Chalupa

doi:10.1016/0165-3806(87)90252-5

Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex

S. H.C. Hendry, E. G. Jones, H. P. Killackey, L. M. Chalupa

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Two monoclonal antibodies to choline acetyltransferase (ChAT) were used to stain the cerebral cortex of fetal monkeys at 110-150 days post-conception. In addition to a small number of immunostained fibers, cells resembling typical non-pyramidal neurons were immunostained in developing layers V and VI and in the subjacent white matter of each area examined (sensory-motor and visual areas). ChAT-immunoreactive neurons have not been described in the cerebral cortex of adult primates, but the present observations indicate such neurons exist in the developing primate cortex.

Original language	English (US)
Pages (from-to)	313-317
Number of pages	5
Journal	Developmental Brain Research
Volume	37
Issue number	1-2
DOIs	https://doi.org/10.1016/0165-3806(87)90252-5
State	Published - Dec 15 1987
Externally published	Yes

Keywords

Acetylcholine
Cerebral cortex
Immunocytochemistry
Non-pyramidal neuron

ASJC Scopus subject areas

Developmental Neuroscience
Developmental Biology

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10.1016/0165-3806(87)90252-5

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title = "Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex",

abstract = "Two monoclonal antibodies to choline acetyltransferase (ChAT) were used to stain the cerebral cortex of fetal monkeys at 110-150 days post-conception. In addition to a small number of immunostained fibers, cells resembling typical non-pyramidal neurons were immunostained in developing layers V and VI and in the subjacent white matter of each area examined (sensory-motor and visual areas). ChAT-immunoreactive neurons have not been described in the cerebral cortex of adult primates, but the present observations indicate such neurons exist in the developing primate cortex.",

keywords = "Acetylcholine, Cerebral cortex, Immunocytochemistry, Non-pyramidal neuron",

author = "Hendry, {S. H.C.} and Jones, {E. G.} and Killackey, {H. P.} and Chalupa, {L. M.}",

note = "Funding Information: 9 HedreenJ,. C., Bacon,S .J., Cork,L .C., Kitt, C.A., Craw-ford, G.D., SalvaterraP,. M. and PriceD, .L., Immuno-cytochemicaidl entificatioonf cholinerginc eurons in the monkeyc entranl ervouss ystem usinmgo noclonaaln tibo-dieaa gainstc holinea cetyltransferaNseeu, rosci.L ett.,43 Supported by Grants EY06432, NS21377 and RR00169 from the National Instituteso f Health. S.H.C.H. is an Alfred P. Sloan Foundation Fellow.",

year = "1987",

month = dec,

day = "15",

doi = "10.1016/0165-3806(87)90252-5",

language = "English (US)",

volume = "37",

pages = "313--317",

journal = "Developmental Brain Research",

issn = "0165-3806",

publisher = "Elsevier B.V.",

number = "1-2",

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TY - JOUR

T1 - Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex

AU - Hendry, S. H.C.

AU - Jones, E. G.

AU - Killackey, H. P.

AU - Chalupa, L. M.

N1 - Funding Information: 9 HedreenJ,. C., Bacon,S .J., Cork,L .C., Kitt, C.A., Craw-ford, G.D., SalvaterraP,. M. and PriceD, .L., Immuno-cytochemicaidl entificatioonf cholinerginc eurons in the monkeyc entranl ervouss ystem usinmgo noclonaaln tibo-dieaa gainstc holinea cetyltransferaNseeu, rosci.L ett.,43 Supported by Grants EY06432, NS21377 and RR00169 from the National Instituteso f Health. S.H.C.H. is an Alfred P. Sloan Foundation Fellow.

PY - 1987/12/15

Y1 - 1987/12/15

N2 - Two monoclonal antibodies to choline acetyltransferase (ChAT) were used to stain the cerebral cortex of fetal monkeys at 110-150 days post-conception. In addition to a small number of immunostained fibers, cells resembling typical non-pyramidal neurons were immunostained in developing layers V and VI and in the subjacent white matter of each area examined (sensory-motor and visual areas). ChAT-immunoreactive neurons have not been described in the cerebral cortex of adult primates, but the present observations indicate such neurons exist in the developing primate cortex.

AB - Two monoclonal antibodies to choline acetyltransferase (ChAT) were used to stain the cerebral cortex of fetal monkeys at 110-150 days post-conception. In addition to a small number of immunostained fibers, cells resembling typical non-pyramidal neurons were immunostained in developing layers V and VI and in the subjacent white matter of each area examined (sensory-motor and visual areas). ChAT-immunoreactive neurons have not been described in the cerebral cortex of adult primates, but the present observations indicate such neurons exist in the developing primate cortex.

KW - Acetylcholine

KW - Cerebral cortex

KW - Immunocytochemistry

KW - Non-pyramidal neuron

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SN - 0165-3806

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EP - 317

JO - Developmental Brain Research

JF - Developmental Brain Research

IS - 1-2

ER -

Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex

Abstract

Keywords

ASJC Scopus subject areas

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