Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex

S. H.C. Hendry, E. G. Jones, H. P. Killackey, L. M. Chalupa

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


Two monoclonal antibodies to choline acetyltransferase (ChAT) were used to stain the cerebral cortex of fetal monkeys at 110-150 days post-conception. In addition to a small number of immunostained fibers, cells resembling typical non-pyramidal neurons were immunostained in developing layers V and VI and in the subjacent white matter of each area examined (sensory-motor and visual areas). ChAT-immunoreactive neurons have not been described in the cerebral cortex of adult primates, but the present observations indicate such neurons exist in the developing primate cortex.

Original languageEnglish (US)
Pages (from-to)313-317
Number of pages5
JournalDevelopmental Brain Research
Issue number1-2
StatePublished - Dec 15 1987
Externally publishedYes


  • Acetylcholine
  • Cerebral cortex
  • Immunocytochemistry
  • Non-pyramidal neuron

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Developmental Biology


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