Chloride Transport Across Vesicle and Cell Membranes by Steroid-Based Receptors

Atanas V. Koulov; Timothy N. Lambert; Rameshwer Shukla; Mahim Jain; J. Middleton Boon; Bradley D. Smith; Hongyu Li; David N. Sheppard; Jean Baptiste Joos; John P. Clare; Anthony P. Davis

doi:10.1002/anie.200351957

Chloride Transport Across Vesicle and Cell Membranes by Steroid-Based Receptors

Atanas V. Koulov
, Timothy N. Lambert
, Rameshwer Shukla
, Mahim Jain
, J. Middleton Boon
, Bradley D. Smith
, Hongyu Li
, David N. Sheppard
, Jean Baptiste Joos
, John P. Clare
, Anthony P. Davis

Research output: Contribution to journal › Article › peer-review

Abstract

Crossing the barriers: Membrane transport, a well-established phenomenon for neutral cation receptors such as valinomycin, has been demonstrated for the anion-binding "cholapods". The cholapods promote chloride efflux from vesicles by an antiport mechanism and mediate anion flow through live cells grown as epithelia (see schematic representation).

Original language	English (US)
Pages (from-to)	4931-4933
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	42
Issue number	40
DOIs	https://doi.org/10.1002/anie.200351957
State	Published - Oct 20 2003
Externally published	Yes

Keywords

Anions
Membranes
Receptors
Steroids
Supramolecular chemistry

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.200351957

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title = "Chloride Transport Across Vesicle and Cell Membranes by Steroid-Based Receptors",

abstract = "Crossing the barriers: Membrane transport, a well-established phenomenon for neutral cation receptors such as valinomycin, has been demonstrated for the anion-binding {"}cholapods{"}. The cholapods promote chloride efflux from vesicles by an antiport mechanism and mediate anion flow through live cells grown as epithelia (see schematic representation).",

keywords = "Anions, Membranes, Receptors, Steroids, Supramolecular chemistry",

author = "Koulov, \{Atanas V.\} and Lambert, \{Timothy N.\} and Rameshwer Shukla and Mahim Jain and Boon, \{J. Middleton\} and Smith, \{Bradley D.\} and Hongyu Li and Sheppard, \{David N.\} and Joos, \{Jean Baptiste\} and Clare, \{John P.\} and Davis, \{Anthony P.\}",

year = "2003",

month = oct,

day = "20",

doi = "10.1002/anie.200351957",

language = "English (US)",

volume = "42",

pages = "4931--4933",

journal = "Angewandte Chemie - International Edition",

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publisher = "John Wiley and Sons Ltd",

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T1 - Chloride Transport Across Vesicle and Cell Membranes by Steroid-Based Receptors

AU - Koulov, Atanas V.

AU - Lambert, Timothy N.

AU - Shukla, Rameshwer

AU - Jain, Mahim

AU - Boon, J. Middleton

AU - Smith, Bradley D.

AU - Li, Hongyu

AU - Sheppard, David N.

AU - Joos, Jean Baptiste

AU - Clare, John P.

AU - Davis, Anthony P.

PY - 2003/10/20

Y1 - 2003/10/20

N2 - Crossing the barriers: Membrane transport, a well-established phenomenon for neutral cation receptors such as valinomycin, has been demonstrated for the anion-binding "cholapods". The cholapods promote chloride efflux from vesicles by an antiport mechanism and mediate anion flow through live cells grown as epithelia (see schematic representation).

AB - Crossing the barriers: Membrane transport, a well-established phenomenon for neutral cation receptors such as valinomycin, has been demonstrated for the anion-binding "cholapods". The cholapods promote chloride efflux from vesicles by an antiport mechanism and mediate anion flow through live cells grown as epithelia (see schematic representation).

KW - Anions

KW - Membranes

KW - Receptors

KW - Steroids

KW - Supramolecular chemistry

UR - https://www.scopus.com/pages/publications/0242386503

UR - https://www.scopus.com/pages/publications/0242386503#tab=citedBy

U2 - 10.1002/anie.200351957

DO - 10.1002/anie.200351957

M3 - Article

C2 - 14579442

AN - SCOPUS:0242386503

SN - 1433-7851

VL - 42

SP - 4931

EP - 4933

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 40

ER -

Chloride Transport Across Vesicle and Cell Membranes by Steroid-Based Receptors

Abstract

Keywords

ASJC Scopus subject areas

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