Chipping Away at Blood-Brain-Barrier Modeling

John J. Jamieson; Sharon Gerecht

doi:10.1016/j.stem.2019.05.014

Chipping Away at Blood-Brain-Barrier Modeling

John J. Jamieson
, Sharon Gerecht

Research output: Contribution to journal › Short survey › peer-review

Abstract

In this issue, Vatine et al. (2019) present a fully human blood-brain barrier chip that accurately predicts drug permeability and can be perfused with whole blood. Utilizing patient-derived tissue, they recapitulate disease-specific defects and establish a platform to advance drug screening and disease modeling.

Original language	English (US)
Pages (from-to)	831-832
Number of pages	2
Journal	Cell stem cell
Volume	24
Issue number	6
DOIs	https://doi.org/10.1016/j.stem.2019.05.014
State	Published - Jun 6 2019
Externally published	Yes

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2019.05.014

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title = "Chipping Away at Blood-Brain-Barrier Modeling",

abstract = "In this issue, Vatine et al. (2019) present a fully human blood-brain barrier chip that accurately predicts drug permeability and can be perfused with whole blood. Utilizing patient-derived tissue, they recapitulate disease-specific defects and establish a platform to advance drug screening and disease modeling.",

author = "Jamieson, \{John J.\} and Sharon Gerecht",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = jun,

day = "6",

doi = "10.1016/j.stem.2019.05.014",

language = "English (US)",

volume = "24",

pages = "831--832",

journal = "Cell stem cell",

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TY - JOUR

T1 - Chipping Away at Blood-Brain-Barrier Modeling

AU - Jamieson, John J.

AU - Gerecht, Sharon

PY - 2019/6/6

Y1 - 2019/6/6

N2 - In this issue, Vatine et al. (2019) present a fully human blood-brain barrier chip that accurately predicts drug permeability and can be perfused with whole blood. Utilizing patient-derived tissue, they recapitulate disease-specific defects and establish a platform to advance drug screening and disease modeling.

AB - In this issue, Vatine et al. (2019) present a fully human blood-brain barrier chip that accurately predicts drug permeability and can be perfused with whole blood. Utilizing patient-derived tissue, they recapitulate disease-specific defects and establish a platform to advance drug screening and disease modeling.

UR - https://www.scopus.com/pages/publications/85066069470

UR - https://www.scopus.com/pages/publications/85066069470#tab=citedBy

U2 - 10.1016/j.stem.2019.05.014

DO - 10.1016/j.stem.2019.05.014

M3 - Short survey

C2 - 31173708

AN - SCOPUS:85066069470

SN - 1934-5909

VL - 24

SP - 831

EP - 832

JO - Cell stem cell

JF - Cell stem cell

IS - 6

ER -

Chipping Away at Blood-Brain-Barrier Modeling

Abstract

ASJC Scopus subject areas

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