@inproceedings{2e02433cbc854d60bd08eb56a3d27f8f,
title = "Chip-based DNA separation in free solution by inertial hydrodynamic forces",
abstract = "We report a microfluidic chip capable of carrying out separations of wide range DNA fragments in free solution by hydrodynamic separation. Hind III digested λ DNA fragments, ranging from 564 to 23,130 bp, were successfully separated in a 2 μm diameter channel by pressure-driven transport. Separations obtained in 15 minutes show the high performance of the device and the specific sizing resolution of small size DNA fragments with 2×105 plate number. To the authors' knowledge, this is the first report on DNA separation on a microfluidic chip without the use of sieving matrices or pulsed electric fields.",
keywords = "Free solution, Hydrodynamic flow, Wide range DNA fragments separation",
author = "Wu, {Jen Kuei} and Sarah Friedrich and Liu, {Kelvin J.} and Wang, {Tza Huei}",
year = "2013",
language = "English (US)",
isbn = "9781632666246",
series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
publisher = "Chemical and Biological Microsystems Society",
pages = "578--580",
booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",
}