Abstract
Colorectal cancer is a major public health concern in all developed countries. Despite decades of advances in the treatment and prevention of colorectal cancer, it remains the second most common cause of cancer death. However, the optimal method for early detection remains unknown and patient compliance with screening recommendations remains poor. This has led to the development of complementary strategies, such as chemoprevention to reduce morbidity and mortality from colorectal cancer. Chemoprevention is defined as the use of specific pharmacologic or nutrient agents to prevent, reverse, or inhibit the process of carcinogenesis. This review was designed to discuss the most promising agents in colorectal chemoprevention.
Original language | English (US) |
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Pages (from-to) | 113-124 |
Number of pages | 12 |
Journal | Diseases of the Colon and Rectum |
Volume | 49 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2006 |
Keywords
- Adenomatous polyps
- Aspirin
- Chemoprevention
- Colorectal cancer
- Nonsteroidal anti-inflammatory drugs
ASJC Scopus subject areas
- Gastroenterology