Characterization of serum acid phosphatase associated with Dengue hemorrhagic fever

K. W. Lam, D. S. Burke, M. Siemens, V. Cipperly, C. Y. Li, L. T. Yam

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Increases of tartrate-resistant acid phosphatase (EC in the serum of children affected by Dengue hemorrhagic fever were detected by a colorimetric method. Immunochemical and electrophoretic methods confirmed that this increased enzyme activity is identical to that of isoenzyme 5b of osteoclasts. Ion-exchange column chromatography separated the serum acid phosphatase into two components with identical antigenicity, substrate specificity, and electrophoretic mobility. They differ in molecular size.

Original languageEnglish (US)
Pages (from-to)2296-2299
Number of pages4
JournalUnknown Journal
Issue number11
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical


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