We have analysed the linkage disequilibrium pattern between the promoter TA microsatellite and Single Nucleotide Polymorphism (SNP) haplotypes for the CYBB gene. None of the CYBB SNPs serve as good surrogates for the microsatellite alleles, previously associated with mild malaria. Thus, the candidate (TA) n microsatellite should be directly tested in genetic epidemiology studies.
|Original language||English (US)|
|Number of pages||3|
|Journal||International Journal of Immunogenetics|
|State||Published - Apr 2008|
ASJC Scopus subject areas
- Molecular Biology