Characterization of a candidate locus for malaria susceptibility in human populations: A (TA)n microsatellite in the promoter region of the CYBB gene, the gp91phox subunit of the NADPH oxidase

G. B. Soares-Souza; E. Tarazona-Santos; S. J. Chanock

doi:10.1111/j.1744-313X.2008.00750.x

Characterization of a candidate locus for malaria susceptibility in human populations: A (TA)_n microsatellite in the promoter region of the CYBB gene, the gp91^phox subunit of the NADPH oxidase

G. B. Soares-Souza, E. Tarazona-Santos, S. J. Chanock

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We have analysed the linkage disequilibrium pattern between the promoter TA microsatellite and Single Nucleotide Polymorphism (SNP) haplotypes for the CYBB gene. None of the CYBB SNPs serve as good surrogates for the microsatellite alleles, previously associated with mild malaria. Thus, the candidate (TA) _n microsatellite should be directly tested in genetic epidemiology studies.

Original language	English (US)
Pages (from-to)	107-109
Number of pages	3
Journal	International Journal of Immunogenetics
Volume	35
Issue number	2
DOIs	https://doi.org/10.1111/j.1744-313X.2008.00750.x
State	Published - Apr 2008
Externally published	Yes

ASJC Scopus subject areas

Immunology
Molecular Biology
Genetics
Genetics(clinical)

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10.1111/j.1744-313X.2008.00750.x

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Characterization of a candidate locus for malaria susceptibility in human populations: A (TA)_n microsatellite in the promoter region of the CYBB gene, the gp91^phox subunit of the NADPH oxidase. / Soares-Souza, G. B.; Tarazona-Santos, E.; Chanock, S. J.
In: International Journal of Immunogenetics, Vol. 35, No. 2, 04.2008, p. 107-109.

Research output: Contribution to journal › Article › peer-review

Soares-Souza, GB, Tarazona-Santos, E & Chanock, SJ 2008, 'Characterization of a candidate locus for malaria susceptibility in human populations: A (TA)_n microsatellite in the promoter region of the CYBB gene, the gp91^phox subunit of the NADPH oxidase', International Journal of Immunogenetics, vol. 35, no. 2, pp. 107-109. https://doi.org/10.1111/j.1744-313X.2008.00750.x

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Characterization of a candidate locus for malaria susceptibility in human populations: A (TA)_n microsatellite in the promoter region of the CYBB gene, the gp91^phox subunit of the NADPH oxidase

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