Characteristics of hospitalized cases of pertussis in Catalonia and Navarra, two regions in the North of Spain

Inma Crespo, Diana Toledo, Núria Soldevila, Iolanda Jordán, Rubén Solano, Jesús Castilla, Joan A. Caylà, Pere Godoy, Carmen Muñoz-Almagro, Ángela Domínguez, Daniela Flavia Hozbor

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Pertussis causes a large number of cases and hospitalizations in Catalonia and Navarra. We made a study of household cases of pertussis during 2012 and 2013 in order to identify risk factors for hospitalization in pertussis cases. Each primary case reported triggered the study of their contacts. Close contacts at home and people who were in contact for >2 hours during the transmission period of cases were included. The adjusted OR and 95% confidence intervals (CI) was calculated using logistic regression. A total of 1124 pertussis cases were detected, of which 14.9% were hospitalized. Inspiratory whoop (aOR: 1.64; CI: 1.02-2.65), apnoea (aOR: 2.47; CI: 1.51-4.03) and cyanosis (aOR: 15.51; CI: 1.87-128.09) were more common in hospitalized than in outpatient cases. Hospitalization occurred in 8.7% of correctly-vaccinated cases, 41.1% of non-vaccinated cases and 9.4% of partially-vaccinated cases. In conclusion, inspiratory whoop, apnoea and cyanosis were associated factors to hospitalization while vaccination reduced hospitalizations due to pertussis.

Original languageEnglish (US)
Article numbere139993
JournalPloS one
Issue number10
StatePublished - Oct 6 2015

ASJC Scopus subject areas

  • General


Dive into the research topics of 'Characteristics of hospitalized cases of pertussis in Catalonia and Navarra, two regions in the North of Spain'. Together they form a unique fingerprint.

Cite this