Changes in maternal serum thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women

Nicolaos Vitoratos; Nikos F. Vlahos; Emanuel Economou; Konstatninos Panoulis; George Creatsas

doi:10.3109/10641955.2010.544800

Changes in maternal serum thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women

Nicolaos Vitoratos, Nikos F. Vlahos, Emanuel Economou, Konstatninos Panoulis, George Creatsas

Research output: Contribution to journal › Article › peer-review

Abstract

Objective. To investigate changes of maternal plasma thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women. Methods. Ten normotensive women (group A) were compared to 17 women with severe preeclampsia (group B). TRX levels were assessed in maternal plasma, immediately after delivery and 1216 weeks postpartum. Results. There were no differences in plasma TRX levels between the two groups immediately antepartum (p = 0.095). A significant reduction in plasma TRX levels was found immediately following delivery only in normotensive group (117.76 ± 37.19 ng/mL vs. 43.45 ± 21.11 ng/mL, p = 0.002), but not in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 53.82 ± 44.34 ng/mL, p = 0.12). Plasma TRX levels remained unchanged in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 55.37 ± 52.23 ng/mL, p = 0.2) at 1214 weeks postpartum.

Original language	English (US)
Pages (from-to)	140-146
Number of pages	7
Journal	Hypertension in Pregnancy
Volume	31
Issue number	1
DOIs	https://doi.org/10.3109/10641955.2010.544800
State	Published - Feb 2012

Keywords

Antepartum
Postpartum
Preeclampsia
TRX

ASJC Scopus subject areas

Internal Medicine
Obstetrics and Gynecology

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10.3109/10641955.2010.544800

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title = "Changes in maternal serum thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women",

abstract = "Objective. To investigate changes of maternal plasma thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women. Methods. Ten normotensive women (group A) were compared to 17 women with severe preeclampsia (group B). TRX levels were assessed in maternal plasma, immediately after delivery and 1216 weeks postpartum. Results. There were no differences in plasma TRX levels between the two groups immediately antepartum (p = 0.095). A significant reduction in plasma TRX levels was found immediately following delivery only in normotensive group (117.76 ± 37.19 ng/mL vs. 43.45 ± 21.11 ng/mL, p = 0.002), but not in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 53.82 ± 44.34 ng/mL, p = 0.12). Plasma TRX levels remained unchanged in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 55.37 ± 52.23 ng/mL, p = 0.2) at 1214 weeks postpartum.",

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doi = "10.3109/10641955.2010.544800",

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AU - Vitoratos, Nicolaos

AU - Vlahos, Nikos F.

AU - Economou, Emanuel

AU - Panoulis, Konstatninos

AU - Creatsas, George

PY - 2012/2

Y1 - 2012/2

N2 - Objective. To investigate changes of maternal plasma thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women. Methods. Ten normotensive women (group A) were compared to 17 women with severe preeclampsia (group B). TRX levels were assessed in maternal plasma, immediately after delivery and 1216 weeks postpartum. Results. There were no differences in plasma TRX levels between the two groups immediately antepartum (p = 0.095). A significant reduction in plasma TRX levels was found immediately following delivery only in normotensive group (117.76 ± 37.19 ng/mL vs. 43.45 ± 21.11 ng/mL, p = 0.002), but not in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 53.82 ± 44.34 ng/mL, p = 0.12). Plasma TRX levels remained unchanged in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 55.37 ± 52.23 ng/mL, p = 0.2) at 1214 weeks postpartum.

AB - Objective. To investigate changes of maternal plasma thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women. Methods. Ten normotensive women (group A) were compared to 17 women with severe preeclampsia (group B). TRX levels were assessed in maternal plasma, immediately after delivery and 1216 weeks postpartum. Results. There were no differences in plasma TRX levels between the two groups immediately antepartum (p = 0.095). A significant reduction in plasma TRX levels was found immediately following delivery only in normotensive group (117.76 ± 37.19 ng/mL vs. 43.45 ± 21.11 ng/mL, p = 0.002), but not in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 53.82 ± 44.34 ng/mL, p = 0.12). Plasma TRX levels remained unchanged in women with preeclampsia (80.42 ± 59.95 ng/mL vs. 55.37 ± 52.23 ng/mL, p = 0.2) at 1214 weeks postpartum.

KW - Antepartum

KW - Postpartum

KW - Preeclampsia

KW - TRX

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Changes in maternal serum thioredoxin (TRX) levels after delivery in preeclamptic and normotensive pregnant women

Abstract

Keywords

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