Cerebral structure in borderline personality disorder

Peter B. Lucas, David L. Gardner, Rex W. Cowdry, David Pickar

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Computed tomographic (CT) scans of brains of patients with borderline personality disorder and normal volunteers were analyzed for ventricle-brain ratios, third ventricular size, and evidence of frontal lobe atrophy. There were no significant differences between the two groups on any of these measures except for a narrower third ventricle in borderline patients, which could be accounted for by the narrower third ventricle observed in female subjects overall. While borderline patients may show signs of subtle neurological dysfunction, they do not show evidence of structural brain pathology.

Original languageEnglish (US)
Pages (from-to)111-115
Number of pages5
JournalPsychiatry Research
Issue number2
StatePublished - 1989
Externally publishedYes


  • borderline personality disorder
  • Computed tomography
  • ventricle-brain ratio

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)


Dive into the research topics of 'Cerebral structure in borderline personality disorder'. Together they form a unique fingerprint.

Cite this