TY - JOUR
T1 - Cerebral Edema
T2 - Role of Fatty Acid Metabolism of Brain Capillaries
AU - Goldstein, Gary W.
AU - Tanaka, Kay
PY - 1977/3/17
Y1 - 1977/3/17
N2 - To the Editor: Jamaican vomiting sickness and Reye's syndrome are characterized by profound brain edema and coma. Tanaka et al. have confirmed the presence of hypoglycin in patients with Jamaican vomiting sickness (N Engl J Med 295:461, 1976), and Trauner and Nyhan have suggested that the resulting increase in serum fatty acids resembles that seen in Reye's syndrome (N Engl J Med 295:1481, 1976). However, neither the hypoglycemia nor the moderate increase in serum fatty acid levels that occur in both conditions appears to provide an adequate explanation for the devastating neurologic symptoms, as indicated by Dr. Tanaka (N.
AB - To the Editor: Jamaican vomiting sickness and Reye's syndrome are characterized by profound brain edema and coma. Tanaka et al. have confirmed the presence of hypoglycin in patients with Jamaican vomiting sickness (N Engl J Med 295:461, 1976), and Trauner and Nyhan have suggested that the resulting increase in serum fatty acids resembles that seen in Reye's syndrome (N Engl J Med 295:1481, 1976). However, neither the hypoglycemia nor the moderate increase in serum fatty acid levels that occur in both conditions appears to provide an adequate explanation for the devastating neurologic symptoms, as indicated by Dr. Tanaka (N.
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U2 - 10.1056/NEJM197703172961115
DO - 10.1056/NEJM197703172961115
M3 - Letter
C2 - 840248
AN - SCOPUS:0017574704
SN - 0028-4793
VL - 296
SP - 632
EP - 633
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 11
ER -