Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: Comparison with [15O]H2O positron emission tomography in humans

Leif Østergaard; Peter Johannsen; Peter Høst-Poulsen; Peter Vestergaard-Poulsen; Helle Asboe; Antony D. Gee; Søren B. Hansen; Georg E. Cold; Albert Gjedde; Garsten Gyldensted

doi:10.1097/00004647-199809000-00002

Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: Comparison with [¹⁵O]H₂O positron emission tomography in humans

Leif Østergaard, Peter Johannsen, Peter Høst-Poulsen, Peter Vestergaard-Poulsen, Helle Asboe, Antony D. Gee, Søren B. Hansen, Georg E. Cold, Albert Gjedde, Garsten Gyldensted

Research output: Contribution to journal › Review article › peer-review

185 Scopus citations

Abstract

In six young, healthy volunteers, a novel method to determine cerebral blood flow (CBF) using magnetic resonance (MR) bolus tracking was compared with [¹⁵O]H₂O positron emission tomography (PET). The method yielded parametric CBF images with tissue contrast in good agreement with parametric PET CBF images. Introducing a common conversion factor, MR CBF values could be converted into absolute flow rates, allowing comparison of CBF values among normal subjects.

Original language	English (US)
Pages (from-to)	935-940
Number of pages	6
Journal	Journal of Cerebral Blood Flow and Metabolism
Volume	18
Issue number	9
DOIs	https://doi.org/10.1097/00004647-199809000-00002
State	Published - Sep 1998
Externally published	Yes

Keywords

Cerebral blood flow
Dynamic magnetic resonance imaging
Humans susceptibility contrast

ASJC Scopus subject areas

Neurology
Clinical Neurology
Cardiology and Cardiovascular Medicine

Access to Document

10.1097/00004647-199809000-00002

Cite this

Østergaard, L., Johannsen, P., Høst-Poulsen, P., Vestergaard-Poulsen, P., Asboe, H., Gee, A. D., Hansen, S. B., Cold, G. E., Gjedde, A., & Gyldensted, G. (1998). Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: Comparison with [¹⁵O]H₂O positron emission tomography in humans. Journal of Cerebral Blood Flow and Metabolism, 18(9), 935-940. https://doi.org/10.1097/00004647-199809000-00002

Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: Comparison with [¹⁵O]H₂O positron emission tomography in humans. / Østergaard, Leif; Johannsen, Peter; Høst-Poulsen, Peter et al.
In: Journal of Cerebral Blood Flow and Metabolism, Vol. 18, No. 9, 09.1998, p. 935-940.

Research output: Contribution to journal › Review article › peer-review

Østergaard, L, Johannsen, P, Høst-Poulsen, P, Vestergaard-Poulsen, P, Asboe, H, Gee, AD, Hansen, SB, Cold, GE, Gjedde, A & Gyldensted, G 1998, 'Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: Comparison with [¹⁵O]H₂O positron emission tomography in humans', Journal of Cerebral Blood Flow and Metabolism, vol. 18, no. 9, pp. 935-940. https://doi.org/10.1097/00004647-199809000-00002

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