Cerebellar Purkinje cells in male macaques combine sensory and motor information to predict the sensory consequences of active self-motion

Neural basis of the sensory suppression signal required to cancel peripheral vestibular input is not fully understood. Here authors show that cerebellar Purkinje cells combine sensory and motor information to predict the sensory consequences of active self-motion, thereby establishing how vestibular reafference is distinguished to cancel self-generated sensory input.