Centromere index derivation by a novel and convenient approach

H. F.L. Mark, R. Mark, T. Pan, Y. Mark

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A previous study has shown the utility of a-graphics arts tool in deriving chromosome measurements for relative length determination. It is our hypothesis that the same approach also can be used accurately for centromere index determination. Results based on a study of 50 cells and comparisons with values cited in An International System for Human Cytogenetic Nomenclature (ISCN)6 are consistent with this hypothesis. Chromosome morphometry is an important adjunct to conventional cytogenetics in suboptimal banded preparations and/or inadequate specimens such as samples from cancer patients.

Original languageEnglish (US)
Pages (from-to)267-274
Number of pages8
JournalAnnals of Clinical and Laboratory Science
Volume23
Issue number4
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Microbiology
  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology
  • Molecular Biology
  • Hematology
  • Clinical Biochemistry
  • Medical Laboratory Technology

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