@article{416a5691fd0346ea9887c360c6af3d63,
title = "Centroacinar cells: At the center of pancreas regeneration",
abstract = "The process of regeneration serves to heal injury by replacing missing cells. Understanding regeneration can help us replace cell populations lost during disease, such as the insulin-producing β cells lost in diabetic patients. Centroacinar cells (CACs) are a specialized ductal pancreatic cell type that act as progenitors to replace β cells in the zebrafish. However, whether CACs contribute to β-cell regeneration in adult mammals remains controversial. Here we review the current understanding of the role of CACs as endocrine progenitors during regeneration in zebrafish and mammals.",
keywords = "Centroacinar cell, Pancreas, Progenitor, Regeneration, Zebrafish, β cell",
author = "Beer, {Rebecca L.} and Parsons, {Michael J.} and Meritxell Rovira",
note = "Funding Information: Thanks to Dr. Meera Saxena for helpful comments concerning the manuscript, and to Mr. Branden Funkhouser for assistance with graphic illustrations. R. L. B. was supported by NIH Grant F32DK101289 , and M. J. P. was supported by NIH grant R01DK080730 . M. R. has been the recipient of an IDIBAPS Postdoctoral Fellowship-BIOTRACK, supported by the European Community's Seventh Framework Programme (EC FP7/2007-2013) under the Grant agreement number 229673 . Funding Information: Thanks to Dr. Meera Saxena for helpful comments concerning the manuscript, and to Mr. Branden Funkhouser for assistance with graphic illustrations. R. L. B. was supported by NIH Grant F32DK101289, and M. J. P. was supported by NIH grant R01DK080730. M. R. has been the recipient of an IDIBAPS Postdoctoral Fellowship-BIOTRACK, supported by the European Community''s Seventh Framework Programme (EC FP7/2007-2013) under the Grant agreement number 229673. Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",
year = "2016",
month = may,
day = "1",
doi = "10.1016/j.ydbio.2016.02.027",
language = "English (US)",
volume = "413",
pages = "8--15",
journal = "Developmental biology",
issn = "0012-1606",
publisher = "Academic Press Inc.",
number = "1",
}