@article{5dd492f4281040529786f0727d295913,
title = "Central serous chorioretinopathy treatment with a systemic PDE5 and PDE6 inhibitor (sildenafil)",
abstract = "Purpose: Examine the use of systemic phosphodiesterase inhibition (sildenafil) to clear central serous chorioretinopathy (CSCR). Observations: In a long-standing CSCR patient, sildenafil produced a rapid resolution. When discontinued (dechallenge) the CSCR returned. When rechallenged, the CSCR again rapidly disappeared and did not recur in 5 months of continued therapy. Conclusions: AND IMPORTANCE: Systemic sildenafil can cause rapid clearance of CSCR and can augment or replace other treatments.",
keywords = "Central serous chorioretinopathy, PDE5/6 inhibitor, Sildenafil",
author = "Coleman, \{D. Jackson\} and Winston Lee and Suzanne Daly and Breazzano, \{Mark P.\} and Janet Sparrow and Tsang, \{Stephen H.\}",
note = "Funding Information: Supported by the National Eye Institute/National Institutes of Health Grant EY024091 and unrestricted grants from the Triad Foundation, Ithaca, New York and St. Giles Foundation, New York, New York. Funding Information: This study was support, in part, by grants from the National Eye Institute/NIH (Bethesda, Maryland) EY024091 , Triad Foundation, Ithaca, New York and the St. Giles Foundation, New York, New York. Jonas Children's Vision Care is supported by the National Institute of Health 5P30CA013696 , U01 EY030580 , U54OD020351 , R24EY028758 , R24EY027285 , 5P30EY019007 , R01EY018213 , R01EY024698 , R01EY026682 , R21AG050437 , the Schneeweiss Stem Cell Fund, New York State [ SDHDOH01-C32590GG-3450000 ], the Foundation Fighting Blindness New York Regional Research Center Grant [ PPA-1218-0751-COLU ], Nancy \& Kobi Karp, the Crowley Family Funds, The Rosenbaum Family Foundation, Alcon Research Institute, the Gebroe Family Foundation, the Research to Prevent Blindness (RPB) Physician-Scientist Award, unrestricted funds from RPB, New York, NY, USA. Publisher Copyright: {\textcopyright} 2020",
year = "2021",
month = mar,
doi = "10.1016/j.ajoc.2020.100998",
language = "English (US)",
volume = "21",
journal = "American Journal of Ophthalmology Case Reports",
issn = "2451-9936",
publisher = "Elsevier Inc.",
}