CD8⁺ T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants

Keyphrases

• Human Immunodeficiency Virus Type 1 (HIV-1) 100%
• CD8+ T Cells 100%
• Escape mutant 100%
• Elite Suppressor 100%
• HLA-B*57 100%
• Escape mutation 83%
• Epitope 50%
• Virus 50%
• Escape Variants 50%
• Cytotoxic T Lymphocytes 33%
• HIV-1 Replication 33%
• HLA-B 33%
• Variant Peptides 33%
• Antiretroviral Therapy 16%
• Viral Replication 16%
• Virologic 16%
• Cytotoxic T Cell Response 16%
• Site-directed mutagenesis 16%
• Limit of Detection 16%
• Plasma Viral Load 16%
• Perforin 16%
• Intracellular Cytokine Staining 16%
• Elite Controllers 16%
• Clinical Assay 16%
• Multiple Lines of Evidence 16%
• Primary CD4+ T Cells 16%

Immunology and Microbiology

• Human Immunodeficiency Virus 1 100%
• Cytotoxic T-Cell 100%
• Epitope 50%
• Wild Type 33%
• Cytotoxic T Cell 33%
• Blood Plasma 33%
• Viral Load 16%
• T-Helper Cell 16%
• Viral Replication 16%
• Site Directed Mutagenesis 16%
• Perforin 16%
• Intracellular Cytokine Staining 16%