Abstract
A man in his 30s with ulcerative colitis (UC) on immunosuppressive agents and extensive travel history presented with subacute dyspnoea and dry cough. CT of the chest demonstrated numerous cavitary pulmonary nodules. An extensive infectious, malignant and autoimmune evaluation was pursued, ultimately with histopathology most consistent with necrobiotic lung nodules as an extraintestinal manifestation of UC. Steroids and ustekinumab were initiated with improvement in symptoms and resolution of cavitary lesions on follow-up imaging. In a patient with inflammatory bowel disease and cavitary lung lesions, necrobiotic lung nodules should be considered, particularly when evaluation for infectious causes is negative.
Original language | English (US) |
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Article number | e251976 |
Journal | BMJ case reports |
Volume | 15 |
Issue number | 9 |
DOIs | |
State | Published - Sep 23 2022 |
Keywords
- Biological agents
- Inflammatory bowel disease
- Respiratory medicine
- Ulcerative colitis
ASJC Scopus subject areas
- General Medicine