Carotid artery atherosclerosis: In vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging - Initial results

Bruce A. Wasserman; William I. Smith; Hugh H. Trout; Richard O. Cannon; Robert S. Balaban; Andrew E. Arai

doi:10.1148/radiol.2232010659

Carotid artery atherosclerosis: In vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging - Initial results

Bruce A. Wasserman, William I. Smith, Hugh H. Trout, Richard O. Cannon, Robert S. Balaban, Andrew E. Arai

School of Medicine

Research output: Contribution to journal › Article › peer-review

260 Scopus citations

Abstract

In nine subjects with carotid atherosclerosis, double-oblique, contrast material-enhanced, double inversion-recovery, fast spin-echo magnetic resonance (MR) images were acquired through atheroma in the proximal internal carotid artery. Fibrocellular tissue within atheroma selectively enhanced 29% after administration of gadolinium-based contrast agent. Contrast enhancement helped discriminate fibrous cap from lipid core with a contrast-to-noise ratio as good as or better than that with T2-weighted MR images but with approximately twice the signal-to-noise ratio (postcontrast images, 36.6 ± 3.6; T2-weighted images, 17.5 ± 2.1; P < .001).

Original language	English (US)
Pages (from-to)	566-573
Number of pages	8
Journal	RADIOLOGY
Volume	223
Issue number	2
DOIs	https://doi.org/10.1148/radiol.2232010659
State	Published - 2002

Keywords

Arteriosclerosis
Magnetic resonance (MR), high-resolution
Magnetic resonance (MR), tissue characterization
Magnetic resonance (MR), vascular studies

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1148/radiol.2232010659

Cite this

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title = "Carotid artery atherosclerosis: In vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging - Initial results",

abstract = "In nine subjects with carotid atherosclerosis, double-oblique, contrast material-enhanced, double inversion-recovery, fast spin-echo magnetic resonance (MR) images were acquired through atheroma in the proximal internal carotid artery. Fibrocellular tissue within atheroma selectively enhanced 29% after administration of gadolinium-based contrast agent. Contrast enhancement helped discriminate fibrous cap from lipid core with a contrast-to-noise ratio as good as or better than that with T2-weighted MR images but with approximately twice the signal-to-noise ratio (postcontrast images, 36.6 ± 3.6; T2-weighted images, 17.5 ± 2.1; P < .001).",

keywords = "Arteriosclerosis, Magnetic resonance (MR), high-resolution, Magnetic resonance (MR), tissue characterization, Magnetic resonance (MR), vascular studies",

author = "Wasserman, {Bruce A.} and Smith, {William I.} and Trout, {Hugh H.} and Cannon, {Richard O.} and Balaban, {Robert S.} and Arai, {Andrew E.}",

year = "2002",

doi = "10.1148/radiol.2232010659",

language = "English (US)",

volume = "223",

pages = "566--573",

journal = "RADIOLOGY",

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publisher = "Radiological Society of North America Inc.",

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TY - JOUR

T1 - Carotid artery atherosclerosis

T2 - In vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging - Initial results

AU - Wasserman, Bruce A.

AU - Smith, William I.

AU - Trout, Hugh H.

AU - Cannon, Richard O.

AU - Balaban, Robert S.

AU - Arai, Andrew E.

PY - 2002

Y1 - 2002

N2 - In nine subjects with carotid atherosclerosis, double-oblique, contrast material-enhanced, double inversion-recovery, fast spin-echo magnetic resonance (MR) images were acquired through atheroma in the proximal internal carotid artery. Fibrocellular tissue within atheroma selectively enhanced 29% after administration of gadolinium-based contrast agent. Contrast enhancement helped discriminate fibrous cap from lipid core with a contrast-to-noise ratio as good as or better than that with T2-weighted MR images but with approximately twice the signal-to-noise ratio (postcontrast images, 36.6 ± 3.6; T2-weighted images, 17.5 ± 2.1; P < .001).

AB - In nine subjects with carotid atherosclerosis, double-oblique, contrast material-enhanced, double inversion-recovery, fast spin-echo magnetic resonance (MR) images were acquired through atheroma in the proximal internal carotid artery. Fibrocellular tissue within atheroma selectively enhanced 29% after administration of gadolinium-based contrast agent. Contrast enhancement helped discriminate fibrous cap from lipid core with a contrast-to-noise ratio as good as or better than that with T2-weighted MR images but with approximately twice the signal-to-noise ratio (postcontrast images, 36.6 ± 3.6; T2-weighted images, 17.5 ± 2.1; P < .001).

KW - Arteriosclerosis

KW - Magnetic resonance (MR), high-resolution

KW - Magnetic resonance (MR), tissue characterization

KW - Magnetic resonance (MR), vascular studies

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Carotid artery atherosclerosis: In vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging - Initial results

Abstract

Keywords

ASJC Scopus subject areas

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