Cardiovascular diseases

J. Bruce Sundstrom, C. Lynne Burek, Noel Richard Rose, Aftab A. Ansari

Research output: Chapter in Book/Report/Conference proceedingChapter


Cardiovascular diseases comprise a broad spectrum of disorders which cause cardiac dysfunction. Vascular diseases such as hypertension, atherosclerosis, and acute and chronic coronary artery disease, which adversely influence systemic hemodynamics, indirectly cause cardiac dysfunction by causing acute myocardial infarction (AMI) or by promoting heart muscle disease. Cardiomyopathies are classified as hypertropic, restrictive, dilated, arrhythmogenic right ventricular, unclassified, or specific. Specific cardiomyopathies describe heart muscle diseases that have been further defined based in part on their etiologies and their association with specific systemic or cardiac disorders. This chapter focuses exclusively on the current knowledge of immunologic aspects involved in the etiology and pathogenesis of cardiomyopathies and the application of immunological and molecular techniques for measuring and characterizing relevant biomarkers used in the detection and assessment of myocardial damage and in determining the diagnosis and prognosis of related cardiovascular diseases.

Original languageEnglish (US)
Title of host publicationManual of Molecular and Clinical Laboratory Immunology
Subtitle of host publication7th edition
PublisherJohn Wiley and Sons Inc.
Number of pages9
ISBN (Electronic)9781683674139
ISBN (Print)9781555813642
StatePublished - Jun 1 2022


  • Acute myocardial infarction (AMI)
  • Cardiomyopathies
  • Cardiovascular diseases
  • Chronic myocardial injury (CMI)
  • Diagnosis

ASJC Scopus subject areas

  • General Medicine
  • General Immunology and Microbiology


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