Cardiac regeneration and stem cell therapy

Joshua M. Hare; Sandra V. Chaparro

doi:10.1097/MOT.0b013e32830fdfc4

Cardiac regeneration and stem cell therapy

Joshua M. Hare, Sandra V. Chaparro

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

PURPOSE OF REVIEW: Significant recent developments have occurred in the field of cardiac regeneration and stem-cell therapy. Understanding the new technological advances in cell therapy will ultimate allow us to achieve a goal of cell-based cardiac repair. RECENT FINDINGS: We discuss the latest cell-based therapies (including skeletal myoblasts, bone-marrow-derived cells, stem cells), the recent clinical trials in humans and different delivery techniques. SUMMARY: Ongoing unraveling of the mechanistic and clinical complexities underlying cardiac regeneration will advance the field of regenerative medicine. Substantial progress is being made by the parallel conduct of basic science studies and clinical trials that are incorporating mechanistic evaluations.

Original language	English (US)
Pages (from-to)	536-542
Number of pages	7
Journal	Current Opinion in Organ Transplantation
Volume	13
Issue number	5
DOIs	https://doi.org/10.1097/MOT.0b013e32830fdfc4
State	Published - Oct 2008
Externally published	Yes

Keywords

Cardiac regeneration
Cell-based therapies
Stem cells

ASJC Scopus subject areas

Immunology and Allergy
Transplantation

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10.1097/MOT.0b013e32830fdfc4

Cite this

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AU - Chaparro, Sandra V.

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AB - PURPOSE OF REVIEW: Significant recent developments have occurred in the field of cardiac regeneration and stem-cell therapy. Understanding the new technological advances in cell therapy will ultimate allow us to achieve a goal of cell-based cardiac repair. RECENT FINDINGS: We discuss the latest cell-based therapies (including skeletal myoblasts, bone-marrow-derived cells, stem cells), the recent clinical trials in humans and different delivery techniques. SUMMARY: Ongoing unraveling of the mechanistic and clinical complexities underlying cardiac regeneration will advance the field of regenerative medicine. Substantial progress is being made by the parallel conduct of basic science studies and clinical trials that are incorporating mechanistic evaluations.

KW - Cardiac regeneration

KW - Cell-based therapies

KW - Stem cells

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Cardiac regeneration and stem cell therapy

Abstract

Keywords

ASJC Scopus subject areas

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