Cardiac manifestations of HIV infection in infants and children

Marcie J. Keesler, Stacy D. Fisher, Steven E. Lipshultz

Research output: Contribution to journalArticlepeer-review

Abstract

Cardiac manifestations of HIV infection in children are common, but etiologies, contributing factors, and the natural history are largely unexplored. The Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted Human Immunodeficiency Virus Infection Study (P2C2 HIV Study) was initiated in 1989 by the National Heart, Lung and Blood Institute, USA. A primary objective of this study is to examine the epidemiology of cardiovascular problems associated with HIV infection in a cohort of children vertically infected. Findings of the study thus far show that cardiovascular problems associated with HIV infection including left ventricular dysfunction and increased left ventricular mass are common and clinically important indicators of survival for children infected with HIV.

Original languageEnglish (US)
Pages (from-to)169-178
Number of pages10
JournalAnnals of the New York Academy of Sciences
Volume946
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • AIDS
  • Cardiovascular
  • Congestive heart failure
  • HIV
  • Pediatric cardiomyopathy

ASJC Scopus subject areas

  • General Neuroscience
  • General Biochemistry, Genetics and Molecular Biology
  • History and Philosophy of Science

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