Carcinoma in situ of the vulva

Joseph Buscema, Donald Woodruff, T. H. Parmley, R. Genadry

Research output: Contribution to journalArticlepeer-review

154 Scopus citations


Of 106 patients with carcinoma in situ (CIS) of the vulva, 102 have been followed from 1 to 15 years. The average age of the patient was 47 years; however, 40% were under the age of 41. Twenty-seven percent had associated cervical malignancy. Only 4 patients developed invasive cancer. Of these, 2 were postmenopausal and the 2 younger patients had been immunosuppessed becasue of systemic disease; thus the subsequent invasive cancer. The incidence of recurrence was essentially the same whether the patient was treated by vulvectomy or wide local excision. In view of the uncertainties about the invasive potential of CIS of the vulva in young patients and the absence of a proved need for an extensive procedure, it is suggested that this entity be treated only by local excision.

Original languageEnglish (US)
Pages (from-to)225-230
Number of pages6
JournalObstetrics and gynecology
Issue number2
StatePublished - Feb 1980

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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