Carbon dioxide prevents pulmonary overcirculation in hypoplastic left heart syndrome

David R. Jobes; Susan C. Nicolson; James M. Steven; Margaret Miller; Marshall L. Jacobs; William I. Norwood

doi:10.1016/0003-4975(92)91166-7

Carbon dioxide prevents pulmonary overcirculation in hypoplastic left heart syndrome

David R. Jobes, Susan C. Nicolson, James M. Steven, Margaret Miller, Marshall L. Jacobs, William I. Norwood

Research output: Contribution to journal › Article › peer-review

97 Scopus citations

Abstract

Circulatory and metabolic homeostasis in patients with hypoplastic left heart syndrome is dependent on a delicate balance between systemic and pulmonary blood flow. Hypocarbia can result in a marked decrease in pulmonary vascular resistance accompanied by pulmonary overcirculation, systemic hypotension, metabolic acidosis, and death. This report illustrates that early and precise control of the arterial carbon dioxide tension using inspired carbon dioxide can be effective in preventing or treating instability arising during management of a patient with hypoplastic left heart syndrome.

Original language	English (US)
Pages (from-to)	150-151
Number of pages	2
Journal	The Annals of thoracic surgery
Volume	54
Issue number	1
DOIs	https://doi.org/10.1016/0003-4975(92)91166-7
State	Published - Jul 1992
Externally published	Yes

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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10.1016/0003-4975(92)91166-7

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abstract = "Circulatory and metabolic homeostasis in patients with hypoplastic left heart syndrome is dependent on a delicate balance between systemic and pulmonary blood flow. Hypocarbia can result in a marked decrease in pulmonary vascular resistance accompanied by pulmonary overcirculation, systemic hypotension, metabolic acidosis, and death. This report illustrates that early and precise control of the arterial carbon dioxide tension using inspired carbon dioxide can be effective in preventing or treating instability arising during management of a patient with hypoplastic left heart syndrome.",

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AU - Nicolson, Susan C.

AU - Steven, James M.

AU - Miller, Margaret

AU - Jacobs, Marshall L.

AU - Norwood, William I.

PY - 1992/7

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AB - Circulatory and metabolic homeostasis in patients with hypoplastic left heart syndrome is dependent on a delicate balance between systemic and pulmonary blood flow. Hypocarbia can result in a marked decrease in pulmonary vascular resistance accompanied by pulmonary overcirculation, systemic hypotension, metabolic acidosis, and death. This report illustrates that early and precise control of the arterial carbon dioxide tension using inspired carbon dioxide can be effective in preventing or treating instability arising during management of a patient with hypoplastic left heart syndrome.

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Carbon dioxide prevents pulmonary overcirculation in hypoplastic left heart syndrome

Abstract

ASJC Scopus subject areas

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