Cancer genetics: Tumor suppressor meets oncogene

Eric R. Fearon, Chi V. Dang

Research output: Contribution to journalComment/debatepeer-review

33 Scopus citations


The adenomatous polyposis coli (APC) tumor suppressor protein is inactivated by mutations in the majority of colorectal cancers. A recent study has revealed that alterations in the APC signaling pathway can result in the transcriptional activation of the c-MYC gene.

Original languageEnglish (US)
Pages (from-to)R62-R65
JournalCurrent Biology
Issue number2
StatePublished - Jan 28 1999

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology


Dive into the research topics of 'Cancer genetics: Tumor suppressor meets oncogene'. Together they form a unique fingerprint.

Cite this