Calcium orchestrates apoptosis

Mark P. Mattson, Sic L. Chan

Research output: Contribution to journalArticlepeer-review

338 Scopus citations


Apoptosis is a feature of many diseases and is critical for the sculpting and maintenance of tissues. New work demonstrates that calcium released from the endoplasmic reticulum synchronizes the mass exodus of cytochrome c from the mitochondria, a phenomenon that coordinates apoptosis.

Original languageEnglish (US)
Pages (from-to)1041-1043
Number of pages3
JournalNature Cell Biology
Issue number12
StatePublished - Dec 2003
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology


Dive into the research topics of 'Calcium orchestrates apoptosis'. Together they form a unique fingerprint.

Cite this