Caffeine

D. P. Evatt; R. R. Griffiths

doi:10.1016/B978-0-12-375083-9.00033-7

Caffeine

D. P. Evatt
, R. R. Griffiths

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Caffeine, an adenosine antagonist, is the most widely used mood-altering drug in the world. Caffeine is rapidly absorbed and distributed throughout the body with peak plasma concentrations typically reached 30-45 min after ingestion. The average half-life of caffeine is 4-6 h. Genetics account for some of the variability in responses to caffeine and individual differences in caffeine pharmacokinetics. Caffeine can function as a reinforcer and produces a wide range of physiological, behavioral, and subjective effects, including anxiety, insomnia, diuresis, alertness, and enhancement in some types of performance. Regular caffeine consumption can produce tolerance, withdrawal, and a substance dependence syndrome.

Original language	English (US)
Title of host publication	Encyclopedia of Human Nutrition
Publisher	Elsevier Inc.
Pages	221-227
Number of pages	7
Volume	1-4
ISBN (Electronic)	9780123848857
ISBN (Print)	9780123750839
DOIs	https://doi.org/10.1016/B978-0-12-375083-9.00033-7
State	Published - Jan 1 2012

Keywords

Anxiety
Caffeine
Dependence
Exercise
Genetics
Mood
Performance
Pharmacokinetics
Reinforcement
Sleep
Tolerance
Withdrawal

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-12-375083-9.00033-7

Cite this

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AB - Caffeine, an adenosine antagonist, is the most widely used mood-altering drug in the world. Caffeine is rapidly absorbed and distributed throughout the body with peak plasma concentrations typically reached 30-45 min after ingestion. The average half-life of caffeine is 4-6 h. Genetics account for some of the variability in responses to caffeine and individual differences in caffeine pharmacokinetics. Caffeine can function as a reinforcer and produces a wide range of physiological, behavioral, and subjective effects, including anxiety, insomnia, diuresis, alertness, and enhancement in some types of performance. Regular caffeine consumption can produce tolerance, withdrawal, and a substance dependence syndrome.

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KW - Caffeine

KW - Dependence

KW - Exercise

KW - Genetics

KW - Mood

KW - Performance

KW - Pharmacokinetics

KW - Reinforcement

KW - Sleep

KW - Tolerance

KW - Withdrawal

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BT - Encyclopedia of Human Nutrition

PB - Elsevier Inc.

ER -

Caffeine

Abstract

Keywords

ASJC Scopus subject areas

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