C1' acylated derivatives of 2'-deoxyuridine, photolabile precursors of 2'-deoxyuridin-1'-yl

Marc M. Greenberg; Dong Jin Yoo; Brian K. Goodman

doi:10.1080/07328319708002519

C1' acylated derivatives of 2'-deoxyuridine, photolabile precursors of 2'-deoxyuridin-1'-yl

Marc M. Greenberg
, Dong Jin Yoo
, Brian K. Goodman

Research output: Contribution to journal › Article › peer-review

Abstract

C1' acylated derivatives of 2'-deoxyuridine (1a-c) were synthesized from 1-[3-deoxy-β-D-psicofuranosyl]uracil (6). The acyl group is introduced via the C1' aldehyde (11). Following nucleophilic addition, the ketones (1a-c) are obtained via periodinane oxidation and desilylation with NH₄F.

Original language	English (US)
Pages (from-to)	33-40
Number of pages	8
Journal	Nucleosides and Nucleotides
Volume	16
Issue number	1-2
DOIs	https://doi.org/10.1080/07328319708002519
State	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Genetics

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10.1080/07328319708002519

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title = "C1' acylated derivatives of 2'-deoxyuridine, photolabile precursors of 2'-deoxyuridin-1'-yl",

abstract = "C1' acylated derivatives of 2'-deoxyuridine (1a-c) were synthesized from 1-[3-deoxy-β-D-psicofuranosyl]uracil (6). The acyl group is introduced via the C1' aldehyde (11). Following nucleophilic addition, the ketones (1a-c) are obtained via periodinane oxidation and desilylation with NH4F.",

author = "Greenberg, \{Marc M.\} and Yoo, \{Dong Jin\} and Goodman, \{Brian K.\}",

year = "1997",

doi = "10.1080/07328319708002519",

language = "English (US)",

volume = "16",

pages = "33--40",

journal = "Nucleosides and Nucleotides",

issn = "0732-8311",

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T1 - C1' acylated derivatives of 2'-deoxyuridine, photolabile precursors of 2'-deoxyuridin-1'-yl

AU - Greenberg, Marc M.

AU - Yoo, Dong Jin

AU - Goodman, Brian K.

PY - 1997

Y1 - 1997

N2 - C1' acylated derivatives of 2'-deoxyuridine (1a-c) were synthesized from 1-[3-deoxy-β-D-psicofuranosyl]uracil (6). The acyl group is introduced via the C1' aldehyde (11). Following nucleophilic addition, the ketones (1a-c) are obtained via periodinane oxidation and desilylation with NH4F.

AB - C1' acylated derivatives of 2'-deoxyuridine (1a-c) were synthesized from 1-[3-deoxy-β-D-psicofuranosyl]uracil (6). The acyl group is introduced via the C1' aldehyde (11). Following nucleophilic addition, the ketones (1a-c) are obtained via periodinane oxidation and desilylation with NH4F.

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U2 - 10.1080/07328319708002519

DO - 10.1080/07328319708002519

M3 - Article

AN - SCOPUS:8044258983

SN - 0732-8311

VL - 16

SP - 33

EP - 40

JO - Nucleosides and Nucleotides

JF - Nucleosides and Nucleotides

IS - 1-2

ER -

C1' acylated derivatives of 2'-deoxyuridine, photolabile precursors of 2'-deoxyuridin-1'-yl

Abstract

ASJC Scopus subject areas

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