TY - JOUR
T1 - C-reactive protein in cardiovascular risk assessment
T2 - a review of the evidence.
AU - Abraham, Jacob
AU - Campbell, Catherine Y.
AU - Cheema, Aamir
AU - Gluckman, T. J.
AU - Blumenthal, Roger S.
AU - Danyi, Peter
N1 - Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 2007
Y1 - 2007
N2 - C-reactive protein (CRP) is an inflammatory biomarker that is strongly associated with coronary heart disease, inflammation, and the metabolic syndrome. Large-scale prospective cohort trials have shown that measurement of CRP may add predictive accuracy to the Framingham risk score, but interpretation of these data are conflicting. In the primary prevention setting, CRP can be used to reclassify patients in low or intermediate Framingham risk score groups to a higher risk category, thus making them eligible for more intensive pharmacologic interventions.
AB - C-reactive protein (CRP) is an inflammatory biomarker that is strongly associated with coronary heart disease, inflammation, and the metabolic syndrome. Large-scale prospective cohort trials have shown that measurement of CRP may add predictive accuracy to the Framingham risk score, but interpretation of these data are conflicting. In the primary prevention setting, CRP can be used to reclassify patients in low or intermediate Framingham risk score groups to a higher risk category, thus making them eligible for more intensive pharmacologic interventions.
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U2 - 10.1111/j.1559-4564.2007.05950.x
DO - 10.1111/j.1559-4564.2007.05950.x
M3 - Review article
C2 - 17684461
AN - SCOPUS:34548397201
SN - 1559-4564
VL - 2
SP - 119
EP - 123
JO - Journal of the cardiometabolic syndrome
JF - Journal of the cardiometabolic syndrome
IS - 2
ER -