TY - JOUR
T1 - Burkitt's and Other Non-Hodgkin's Lymphomas in Adults Exposed to a Visitor from Africa
AU - Grufferman, Seymour
AU - Raab-Traub, Nancy
AU - Marvin, Kay
AU - Borowitz, Michael J.
AU - Pagano, Joseph S.
PY - 1985/12/12
Y1 - 1985/12/12
N2 - DISEASE clustering, the occurrence of cases that are close together in time and space, is often believed to suggest an infectious cause.1,2 Despite numerous anecdotal reports of cancer clusters, Burkitt's lymphoma is the only human cancer for which there is clear-cut statistical evidence of time—space clustering.2 3 4 In general, reports of cancer clusters are uninformative, since most cancers have long, variable, or unknown latency periods between etiologic exposure and manifestation of the disease.2,4,5 A typical reported cluster is characterized by proximity in the time of diagnosis and in the residence of patients at diagnosis. However, the etiologic exposure may have occurred.
AB - DISEASE clustering, the occurrence of cases that are close together in time and space, is often believed to suggest an infectious cause.1,2 Despite numerous anecdotal reports of cancer clusters, Burkitt's lymphoma is the only human cancer for which there is clear-cut statistical evidence of time—space clustering.2 3 4 In general, reports of cancer clusters are uninformative, since most cancers have long, variable, or unknown latency periods between etiologic exposure and manifestation of the disease.2,4,5 A typical reported cluster is characterized by proximity in the time of diagnosis and in the residence of patients at diagnosis. However, the etiologic exposure may have occurred.
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U2 - 10.1056/NEJM198512123132407
DO - 10.1056/NEJM198512123132407
M3 - Article
C2 - 2999593
AN - SCOPUS:0022348688
SN - 0028-4793
VL - 313
SP - 1525
EP - 1529
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 24
ER -