TY - JOUR
T1 - Burden and risk factors of chronic respiratory diseases in Nepal, 1990–2019
T2 - An analysis of the global burden of diseases study
AU - Adhikari, Tara Ballav
AU - Paudel, Kiran
AU - Paudel, Rajan
AU - Bhusal, Sandesh
AU - Rijal, Anupa
AU - Högman, Marieann
AU - Neupane, Dinesh
AU - Sigsgaard, Torben
AU - Kallestrup, Per
N1 - Funding Information:
The authors are grateful to the Institute of Health Metrics Evaluation (IHME), Global Burden of Disease Study 2019 team for making the data available.
Publisher Copyright:
© 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC.
PY - 2023/2
Y1 - 2023/2
N2 - Background and Aims: Chronic respiratory diseases (CRDs) substantially contribute to morbidity and mortality globally and in Nepal. However, there is a paucity of evidence on the trend and the burden of CRDs in Nepal. This study reports the trend of the burden and contribution of major risk factors to CRDs in Nepal from 1990 to 2019. Methods: This study is an observational study using publicly available data from Global Burden of Disease 2019 estimations for Nepal. The age-standardized and age-specific prevalence, incidence, mortality, disability-adjusted life years (DALYs), and risk factors for CRDs in Nepal were extracted to measure the burden and its trend. The data are presented as percentages or as rates per 100,000 population. Results: The age-standardized incidence rate of CRDs in Nepal in 2019 was 913.6 per 100,000 (95% uncertainty interval [UI]: 828.7–1000.1), which was an increase of 7.7% from 848.6 per 100,000 (95% UI: 780.2–918.2) in 1990. However, the age-standardized prevalence rate [4453/100,000 (4234.2–4671.8) in 1990; 4457.1/100,000 (4255.2–4666.8) in 2019] was almost stagnant. Most CRDs attributed to deaths and DALYs were due to chronic obstructive pulmonary disease. Conclusions: Air pollution and smoking are the main risk factors for DALYs due to CRDs in Nepal. This surging burden of the incidence rate of CRDs in Nepal calls for more effective actions to curb the risk factors and diseases.
AB - Background and Aims: Chronic respiratory diseases (CRDs) substantially contribute to morbidity and mortality globally and in Nepal. However, there is a paucity of evidence on the trend and the burden of CRDs in Nepal. This study reports the trend of the burden and contribution of major risk factors to CRDs in Nepal from 1990 to 2019. Methods: This study is an observational study using publicly available data from Global Burden of Disease 2019 estimations for Nepal. The age-standardized and age-specific prevalence, incidence, mortality, disability-adjusted life years (DALYs), and risk factors for CRDs in Nepal were extracted to measure the burden and its trend. The data are presented as percentages or as rates per 100,000 population. Results: The age-standardized incidence rate of CRDs in Nepal in 2019 was 913.6 per 100,000 (95% uncertainty interval [UI]: 828.7–1000.1), which was an increase of 7.7% from 848.6 per 100,000 (95% UI: 780.2–918.2) in 1990. However, the age-standardized prevalence rate [4453/100,000 (4234.2–4671.8) in 1990; 4457.1/100,000 (4255.2–4666.8) in 2019] was almost stagnant. Most CRDs attributed to deaths and DALYs were due to chronic obstructive pulmonary disease. Conclusions: Air pollution and smoking are the main risk factors for DALYs due to CRDs in Nepal. This surging burden of the incidence rate of CRDs in Nepal calls for more effective actions to curb the risk factors and diseases.
KW - DALYs
KW - Nepal
KW - chronic respiratory diseases
KW - incidence
KW - mortality
KW - prevalence
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U2 - 10.1002/hsr2.1091
DO - 10.1002/hsr2.1091
M3 - Article
C2 - 36741854
AN - SCOPUS:85149199415
SN - 2398-8835
VL - 6
JO - Health Science Reports
JF - Health Science Reports
IS - 2
M1 - e1091
ER -