TY - JOUR
T1 - Building an integrated serosurveillance platform to inform public health interventions
T2 - Insights from an experts’ meeting on serum biomarkers
AU - Collaboration on Integrated Biomarkers Surveillance
AU - Wiens, Kirsten E.
AU - Jauregui, Barbara
AU - Arnold, Benjamin F.
AU - Banke, Kathryn
AU - Wade, Djibril
AU - Hayford, Kyla
AU - Denis, Adriana Costero Saint
AU - Hall, Robert H.
AU - Salje, Henrik
AU - Rodriguez-Barraquer, Isabel
AU - Azman, Andrew S.
AU - Vernet, Guy
AU - Leung, Daniel T.
N1 - Publisher Copyright:
© Public Library of Science.
PY - 2022/10/6
Y1 - 2022/10/6
N2 - The use of biomarkers to measure immune responses in serum is crucial for understanding population-level exposure and susceptibility to human pathogens. Advances in sample collection, multiplex testing, and computational modeling are transforming serosurveillance into a powerful tool for public health program design and response to infectious threats. In July 2018, 70 scientists from 16 countries met to perform a landscape analysis of approaches that support an integrated serosurveillance platform, including the consideration of issues for successful implementation. Here, we summarize the group’s insights and proposed roadmap for implementation, including objectives, technical requirements, ethical issues, logistical considerations, and monitoring and evaluation.
AB - The use of biomarkers to measure immune responses in serum is crucial for understanding population-level exposure and susceptibility to human pathogens. Advances in sample collection, multiplex testing, and computational modeling are transforming serosurveillance into a powerful tool for public health program design and response to infectious threats. In July 2018, 70 scientists from 16 countries met to perform a landscape analysis of approaches that support an integrated serosurveillance platform, including the consideration of issues for successful implementation. Here, we summarize the group’s insights and proposed roadmap for implementation, including objectives, technical requirements, ethical issues, logistical considerations, and monitoring and evaluation.
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U2 - 10.1371/journal.pntd.0010657
DO - 10.1371/journal.pntd.0010657
M3 - Article
C2 - 36201428
AN - SCOPUS:85139377297
SN - 1935-2727
VL - 16
JO - PLoS neglected tropical diseases
JF - PLoS neglected tropical diseases
IS - 10
M1 - e0010657
ER -