Building a better mosquito: Identifying the genes enabling malaria and dengue fever resistance in A. gambiae and A. aegypti mosquitoes

George Dimopoulos

doi:10.3791/233

Building a better mosquito: Identifying the genes enabling malaria and dengue fever resistance in A. gambiae and A. aegypti mosquitoes

George Dimopoulos

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In this interview, George Dimopoulos focuses on the physiological mechanisms used by mosquitoes to combat Plasmodium falciparum and dengue virus infections. Explanation is given for how key refractory genes, those genes conferring resistance to vector pathogens, are identified in the mosquito and how this knowledge can be used to generate transgenic mosquitoes that are unable to carry the malaria parasite or dengue virus.

Original language	English (US)
Article number	e233
Journal	Journal of Visualized Experiments
Issue number	5
DOIs	https://doi.org/10.3791/233
State	Published - Jun 2007

ASJC Scopus subject areas

Neuroscience(all)
Chemical Engineering(all)
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)

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10.3791/233

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Building a better mosquito: Identifying the genes enabling malaria and dengue fever resistance in A. gambiae and A. aegypti mosquitoes

Abstract

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