Brief report: Pneumocystis carinii osteomyelitis in a patient with common variable immunodeficiency

PNEUMOCYSTIS CARINII is a well-known pulmonary pathogen that has been increasingly identified in extrapulmonary sites in patients with the acquired immunodeficiency syndrome (AIDS).^{1 2 3 4 5 6 7} We describe a case of pneumocystis osteomyelitis that occurred in a patient with common variable immunodeficiency. It was striking that the patient appeared to have normal cell-mediated immunity, including a blastogenic response to pneumocystis antigen. Case Report A 27-year-old black woman with common variable immunodeficiency presented with a one-month history of increasing pain in the left buttock. Common variable immunodeficiency had been diagnosed five years earlier after an evaluation for recurrent infections of the upper and lower.