TY - JOUR
T1 - Brief Report
T2 - A Second Primary Endodermal Sinus Tumor 9 Years after Initial Diagnosis
AU - Moukarzel, Lea A.
AU - Levinson, Kimberly
AU - Grumbine, Francis C.
PY - 2016
Y1 - 2016
N2 - Background: Ovarian yolk sac tumors (YSTs) are rare malignant germ cell tumors known to present unilaterally, allowing for fertility-sparing surgical treatment with adjuvant chemotherapy. The few published cases of bilateral ovarian involvement were at the time of original diagnosis in patients with widely metastatic disease. We present, to our knowledge, the first case of bilateral ovarian YSTs, diagnosed several years apart, and discuss the implications on recurrence and tumor marker surveillance for these tumors. Case: This is a case of a young woman who re-presented 9 years after initial treatment, with a YST in the contralateral ovary. Summary and Conclusions: YSTs are well established as unilateral tumors, however, in rare cases such as this, they might reappear years later on the contralateral ovary.
AB - Background: Ovarian yolk sac tumors (YSTs) are rare malignant germ cell tumors known to present unilaterally, allowing for fertility-sparing surgical treatment with adjuvant chemotherapy. The few published cases of bilateral ovarian involvement were at the time of original diagnosis in patients with widely metastatic disease. We present, to our knowledge, the first case of bilateral ovarian YSTs, diagnosed several years apart, and discuss the implications on recurrence and tumor marker surveillance for these tumors. Case: This is a case of a young woman who re-presented 9 years after initial treatment, with a YST in the contralateral ovary. Summary and Conclusions: YSTs are well established as unilateral tumors, however, in rare cases such as this, they might reappear years later on the contralateral ovary.
KW - Alpha-fetoprotein
KW - Malignant ovarian germ cell tumors
KW - Yolk sac tumors
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U2 - 10.1016/j.jpag.2016.10.012
DO - 10.1016/j.jpag.2016.10.012
M3 - Article
C2 - 27818263
AN - SCOPUS:85008430532
SN - 1083-3188
JO - Journal of Pediatric and Adolescent Gynecology
JF - Journal of Pediatric and Adolescent Gynecology
ER -