TY - JOUR
T1 - Brief communication
T2 - Separation of the complement-fixing and early antigens from Epstein-Barr soluble antigen
AU - Wainwright, William H.
AU - Veitri, Robert W.
N1 - Funding Information:
ABBREVIATIONS USED: EBV = Epstein-Barr virus; CFSA = complement-fixing soluble antigen; EA = early antigen; MA = membrane antigen; VCA = virus capsid antigen; EBNA = Epstein-Barr nuclear antigen; EBSA = Epstein-Barr soluble antigen; IUOR = 5-iodo-2'deoxyuridine; PBS = phosphate-buffered saline. 1 Received June n, 1976; accepted September 27, 1976. 2 Supported by Public Health Service training grant 5TI2 CA8071-09 from the National Cancer Institute and by general research support grants 8610226472 and 863113647 from the West Virginia University School of Medicine and School of Dentistry, respectively. 3Department of Microbiology, West Virginia University Medical Center, Morgantown, W. Va. 26506. 4 Division of Otolaryngology ad Department of Microbiology, West Virginia University Medical Center. 5Address reprint requests to Dr. Veltri at the Division of Otolaryngology.
PY - 1977/4
Y1 - 1977/4
N2 - The Epstein-Barr virus-associated complement-fixing (soluble) antigen (CFSA) and the early antigen (EA) were isolated by ion-exchange chromatography from the P3HR-1 lym-phobiastoid cell line activated with 5-iodo-2′-deoxyuridine for 72 hours. As expected, these two antigens were not immunologically identical. The CFSA, but not the EA, was isolated from the RAJI lymphoblastoid cell line by the same method.
AB - The Epstein-Barr virus-associated complement-fixing (soluble) antigen (CFSA) and the early antigen (EA) were isolated by ion-exchange chromatography from the P3HR-1 lym-phobiastoid cell line activated with 5-iodo-2′-deoxyuridine for 72 hours. As expected, these two antigens were not immunologically identical. The CFSA, but not the EA, was isolated from the RAJI lymphoblastoid cell line by the same method.
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U2 - 10.1093/jnci/58.4.1111
DO - 10.1093/jnci/58.4.1111
M3 - Article
C2 - 66320
AN - SCOPUS:0017354703
SN - 0027-8874
VL - 58
SP - 1111
EP - 1113
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 4
ER -